Disease-gene associations mined from literature

Literature associating RHNO1 and rhinosporidiosis

RHNO1 [ENSP00000479598]

RAD9, HUS1, RAD1-interacting nuclear orphan protein 1; Plays a role in DNA damage response (DDR) signaling upon genotoxic stresses such as ionizing radiation (IR) during the S phase. Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner. Required for the progression of the G1 to S phase transition. Plays a role in the stimulation of CHEK1 phosphorylation.

Synonyms:  RHNO1,  RHNO1p,  hRHNO1,  F5H0U1,  F5H580 ...

Linkouts:  STRING  Pharos  UniProt