DISEASES

Disease-gene associations mined from literature

Literature associating CBY1 and orchitis

CBY1 [ENSP00000478962]

PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation; Belongs to the chibby family.

Synonyms:  CBY1,  CBY1p,  hCBY1,  A0A024R1L9,  B0QY53 ...

Linkouts:  STRING  Pharos  UniProt