DISEASES

Disease-gene associations mined from literature

Literature associating CCL16 and visceral leishmaniasis

CCL16 [ENSP00000478024]

Lymphocyte and monocyte chemoattractant; Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES; Belongs to the intercrine beta (chemokine CC) family.

Synonyms:  CCL16,  CCL16p,  hCCL16,  K7ELY7,  ILINCK ...

Linkouts:  STRING  Pharos