Disease-gene associations mined from literature

Literature associating HIST1H2BM and tonsil squamous cell carcinoma

HIST1H2BM [ENSP00000477907]

Histone cluster 1, H2bm; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms:  HIST1H2BM,  I6L9F7,  Q99879,  H2BFE,  I6L9F7p ...

Linkouts:  STRING  Pharos  UniProt