DISEASES

Disease-gene associations mined from literature

Literature associating KCNN1 and autosomal dominant non-syndromic intellectual disability 29

KCNN1 [ENSP00000476519]

Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity); Belongs to the potassium channel KCNN family. KCa2.1/KCNN1 subfamily.

Synonyms:  KCNN1,  KCNN1p,  hKCNN1,  KCNN1-001,  KCNN1-004 ...

Linkouts:  STRING  Pharos  UniProt