Disease-gene associations mined from literature

Literature associating SLC37A4 and severe congenital neutropenia 5

SLC37A4 [ENSP00000476176]

Solute carrier family 37 (glucose-6-phosphate transporter), member 4; Inorganic phosphate and glucose-6-phosphate antiporter of the endoplasmic reticulum. Transports cytoplasmic glucose-6- phosphate into the lumen of the endoplasmic reticulum and translocates inorganic phosphate into the opposite direction. Forms with glucose-6-phosphatase the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it plays a central role in homeostatic regulation of blood glucose levels; Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.

Synonyms:  SLC37A4,  SLC37A4p,  hSLC37A4,  U3KQV0,  G6PT ...

Linkouts:  STRING  Pharos