DISEASES

Disease-gene associations mined from literature

Literature associating CDC42SE1 and dilated cardiomyopathy 1P

CDC42SE1 [ENSP00000475845]

Small effector of CDC42 protein 1; Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages; Belongs to the CDC42SE/SPEC family.

Synonyms:  CDC42SE1,  Q9NRR8,  Q9NRR8p,  hQ9NRR8,  SPEC1 ...

Linkouts:  STRING  Pharos  UniProt