DISEASES

Disease-gene associations mined from literature

Literature associating DUOX2 and Crohn's disease

DUOX2 [ENSP00000475084]

NADH/NADPH thyroid oxidase p138-tox; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.

Synonyms:  DUOX2,  DUOX2p,  hDUOX2,  Q9NRD8,  S6B490 ...

Linkouts:  STRING  Pharos  UniProt