Literature associating DUOX2 and hypothyroidism
NADH/NADPH thyroid oxidase p138-tox; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Synonyms: DUOX2, DUOX2p, hDUOX2, Q9NRD8, S6B490 ...