Literature associating FPR1 and aggressive periodontitis
N-formylpeptide chemoattractant receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system.
Synonyms: FPR1, FPR1p, hFPR1, M0QZT0, M0R315 ...