Literature associating FPR1 and bacterial infectious disease
FPR1 [ENSP00000471493]
fMet-Leu-Phe receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors . Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G- protein that activates a phosphatidylinositol-calcium second messenger system . Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release . ECO:0000269|PubMed:15153520, ECO:0000269|PubMed:2161213, ECO:0000269|PubMed:2176894, ECO:0000269|PubMed:25109685, ECO:0000303|PubMed:10514456, ECO:0000303|PubMed:1712023,
Synonyms: FPR1, FPR1p, hFPR1, M0QZT0, M0R315 ...