DISEASES

Disease-gene associations mined from literature

Literature associating FPR1 and bacterial infectious disease

FPR1 [ENSP00000471493]

N-formylpeptide chemoattractant receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system.

Synonyms:  FPR1,  FPR1p,  hFPR1,  M0QZT0,  M0R315 ...

Linkouts:  STRING  Pharos  UniProt