DISEASES

Disease-gene associations mined from literature

Literature associating CGB7 and Down syndrome

CGB7 [ENSP00000470813]

Chorionic gonadotropin, beta polypeptide 7; Beta subunit of the human chorionic gonadotropin (hCG). hCG is a complex glycoprotein composed of two glycosylated subunits alpha and beta which are non-covalently associated. The alpha subunit is identical to those in the pituitary gonadotropin hormones (LH, FSH and TSH). The beta subunits are distinct in each of the hormones and confer receptor and biological specificity. Has an essential role for pregnancy and maternal adaptation. Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.

Synonyms:  CGB7,  CGB7p,  hCGB7,  CGB,  J3KP00 ...

Linkouts:  STRING  Pharos  UniProt