Literature associating IL12RB1 and immunodeficiency 16
Interleukin-12 receptor subunit beta-1; Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade; CD molecules
Synonyms: IL12RB1, IL12RB1p, hIL12RB1, IL12RB1-001, IL12RB1-002 ...