DISEASES

Disease-gene associations mined from literature

Literature associating FPR2 and prion disease

FPR2 [ENSP00000468897]

Formyl peptide receptor-like 1; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Synonyms:  FPR2,  FPR2p,  hFPR2,  A0A024R4P3,  FPRL1 ...

Linkouts:  STRING  Pharos  UniProt