Literature associating FPR2 and prion disease
Formyl peptide receptor-like 1; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Synonyms: FPR2, FPR2p, hFPR2, A0A024R4P3, FPRL1 ...