DISEASES

Disease-gene associations mined from literature

Literature associating FAM20A and amelogenesis imperfecta

FAM20A [ENSP00000468308]

Family with sequence similarity 20, member A; Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals.

Synonyms:  FAM20A,  FAM20Ap,  hFAM20A,  FAM20A-001,  FAM20A-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM