DISEASES

Disease-gene associations mined from literature

Literature associating MBTD1 and endometrial stromal sarcoma

MBTD1 [ENSP00000468304]

MBT domain-containing protein 1; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility (By similarity). Specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4; MBT domain containing

Synonyms:  MBTD1,  MBTD1p,  hMBTD1,  K7EQ11,  MBTD1-001 ...

Linkouts:  STRING  Pharos  UniProt