Disease-gene associations mined from literature

Literature associating ERC1 and Lambert-Eaton myasthenic syndrome

ERC1 [ENSP00000468263]

ELKS/RAB6-interacting/CAST family member 1; Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport.

Synonyms:  ERC1,  ERC1p,  hERC1,  ERC1-001,  ERC1-002 ...

Linkouts:  STRING  Pharos  UniProt