Literature associating RNF213 and cerebral atherosclerosis
ALK lymphoma oligomerization partner on chromosome 17; E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity; Ring finger proteins
Synonyms: RNF213, RNF213p, hRNF213, H3BLU6, Q63HN8 ...