Literature associating ADCYAP1 and holoprosencephaly 3
Adenylate cyclase activating polypeptide 1 (pituitary); Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity); Belongs to the glucagon family.
Synonyms: ADCYAP1, ADCYAP1p, hADCYAP1, B7Z222, P18509 ...