DISEASES

Disease-gene associations mined from literature

Literature associating ADCYAP1 and pheochromocytoma

ADCYAP1 [ENSP00000462647]

Adenylate cyclase activating polypeptide 1 (pituitary); Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity); Belongs to the glucagon family.

Synonyms:  ADCYAP1,  ADCYAP1p,  hADCYAP1,  B7Z222,  P18509 ...

Linkouts:  STRING  Pharos  UniProt