Disease-gene associations mined from literature

Literature associating PIRT and isolated growth hormone deficiency type IB

PIRT [ENSP00000462046]

Phosphoinositide-interacting regulator of transient receptor potential channels; Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5- bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity).

Synonyms:  PIRT,  P0C851,  P0C851p,  hP0C851,  644139 ...

Linkouts:  STRING  Pharos  UniProt  OMIM