Literature associating PIRT and isolated growth hormone deficiency type IB
Phosphoinositide-interacting regulator of transient receptor potential channels; Regulatory subunit of TRPV1, a molecular sensor of noxious heat and capsaicin. Positively regulates TRPV1 channel activity via phosphatidylinositol 4,5-bisphosphate (PIP2). Binds various phosphoinositide, including phosphatidylinositol 4,5- bisphosphate (PIP2), but not phosphatidylinositol (PI) (By similarity).
Synonyms: PIRT, P0C851, P0C851p, hP0C851, 644139 ...