DISEASES

Disease-gene associations mined from literature

Literature associating SCIMP and autosomal dominant familial periodic fever

SCIMP [ENSP00000461269]

SLP adapter and CSK-interacting membrane protein; Lipid tetraspanin-associated transmembrane adapter/mediator involved in major histocompatibility complex (MHC) class II signaling transduction. Required in generating the calcium response and enhancing ERK activity upon MHC-II stimulation.

Synonyms:  SCIMP,  I3L1W2,  Q6UWF3,  C17orf87,  I3L1W2p ...

Linkouts:  STRING  Pharos  UniProt