Disease-gene associations mined from literature

Literature associating OST4 and autosomal recessive chronic granulomatous disease cytochrome b-positive type II

OST4 [ENSP00000457935]

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4; Acts as component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for efficient N- glycosylation. Specifically involved in maintaining stability of STT3A-containing OST complexes; Belongs to the OST4 family.

Synonyms:  OST4,  OST4p,  hOST4,  P0C6T2,  P0C6T2p ...

Linkouts:  STRING  Pharos  UniProt