DISEASES

Disease-gene associations mined from literature

Literature associating CHD9 and CHARGE syndrome

CHD9 [ENSP00000457466]

Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein; Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis (By similarity); Belongs to the SNF2/RAD54 helicase family.

Synonyms:  CHD9,  CHD9p,  hCHD9,  B4DR07,  H3BRU9 ...

Linkouts:  STRING  Pharos  UniProt