DISEASES

Disease-gene associations mined from literature

Literature associating LDLR and arcus senilis

LDLR [ENSP00000454071]

Low density lipoprotein receptor; Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits; Belongs to the LDLR family.

Synonyms:  LDLR,  A0A024R7D5,  E1B4S5,  H0YMD1,  P01130 ...

Linkouts:  STRING  Pharos  UniProt  OMIM