Literature associating TLE3 and chromosome 1q21.1 duplication syndrome
Enhancer of split groucho-like protein 3; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity); WD repeat domain containing
Synonyms: TLE3, TLE3p, hTLE3, B4E2W3, F5H7D6 ...