DISEASES

Disease-gene associations mined from literature

Literature associating NDRG2 and intracranial meningioma

NDRG2 [ENSP00000451712]

N-myc downstream-regulated gene 2 protein; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.

Synonyms:  NDRG2,  NDRG2p,  hNDRG2,  G3V237,  G3V239 ...

Linkouts:  STRING  Pharos  UniProt