DISEASES

Disease-gene associations mined from literature

Literature associating PGF and twin-to-twin transfusion syndrome

PGF [ENSP00000451040]

Placental growth factor; Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.

Synonyms:  PGF,  G3XA84,  P49763,  Q53XY6,  G3XA84p ...

Linkouts:  STRING  Pharos  UniProt  OMIM