Disease-gene associations mined from literature

Literature associating AACT and endometrial adenosquamous carcinoma

AACT [ENSP00000450540]

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2; Serpin peptidase inhibitors

Synonyms:  SERPINA3,  AACT,  GIG24,  GIG25,  12 ...

Linkouts:  STRING  Pharos