DISEASES

Disease-gene associations mined from literature

Literature associating PPFIA2 and X-linked exudative vitreoretinopathy 2

PPFIA2 [ENSP00000450337]

Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2; Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates; Belongs to the liprin family. Liprin-alpha subfamily.

Synonyms:  PPFIA2,  PPFIA2p,  hPPFIA2,  F8VU88,  F8VWG6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM