DISEASES

Disease-gene associations mined from literature

Literature associating BRF1 and Van der Woude syndrome

BRF1 [ENSP00000448323]

TATA box-binding protein-associated factor, RNA polymerase III, subunit 2; General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.

Synonyms:  BRF1,  BRF1p,  hBRF1,  A0A024R6P8,  A3KN61 ...

Linkouts:  STRING  Pharos  UniProt  OMIM