Disease-gene associations mined from literature

Literature associating FRS2 and liposarcoma

FRS2 [ENSP00000447241]

Fibroblast growth factor receptor substrate 2; Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Synonyms:  FRS2,  FRS2p,  hFRS2,  F8VS98,  F8VW66 ...

Linkouts:  STRING  Pharos  UniProt