Literature associating NR1H4 and primary sclerosing cholangitis
NR1H4 [ENSP00000447149]
Nuclear receptor subfamily 1, group H, member 4; Isoform 4: Promotes transcriptional activation of target genes ABCB11/BSEP (inducible by unconjugated CDCA, ACA and DCA), NR0B2/SHP (inducible by unconjugated CDCA, ACA and DCA), SLC51B/OSTB (inducible by unconjugated CDCA and DCA) and FABP6/IBAP; most efficient isoform compared to isoforms 1 to 3; not inducible by taurine- and glycine-amidated CDCA; Belongs to the nuclear hormone receptor family. NR1 subfamily.
Synonyms: NR1H4, NR1H4p, hNR1H4, B6ZGS9, B7Z423 ...