DISEASES

Disease-gene associations mined from literature

Literature associating PRAME and chronic myeloid leukemia

PRAME [ENSP00000445675]

Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis; PRAME family

Synonyms:  PRAME,  F8WF80,  P78395,  F8WF80p,  hF8WF80 ...

Linkouts:  STRING  Pharos  UniProt