DISEASES

Disease-gene associations mined from literature

Literature associating FRY and alcohol-related neurodevelopmental disorder

FRY [ENSP00000445043]

Furry homolog (Drosophila); Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation; Belongs to the furry protein family.

Synonyms:  FRY,  LOC102724531,  214K23.2,  B1ALA1,  F5H4D2 ...

Linkouts:  STRING  Pharos  UniProt