DISEASES

Disease-gene associations mined from literature

Literature associating FKBP5 and mental depression

FKBP5 [ENSP00000444810]

54 kDa progesterone receptor-associated immunophilin; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded; FKBP prolyl isomerases

Synonyms:  FKBP5,  FKBP5p,  hFKBP5,  B7Z7Z8,  FKBP5-001 ...

Linkouts:  STRING  Pharos  UniProt