Literature associating FKBP5 and mental depression
54 kDa progesterone receptor-associated immunophilin; Immunophilin protein with PPIase and co-chaperone activities. Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded; FKBP prolyl isomerases
Synonyms: FKBP5, FKBP5p, hFKBP5, B7Z7Z8, FKBP5-001 ...