DISEASES

Disease-gene associations mined from literature

Literature associating SLCO1C1 and hyperthyroidism

SLCO1C1 [ENSP00000444149]

Solute carrier organic anion transporter family, member 1C1; Mediates the Na(+)-independent high affinity transport of organic anions such as the thyroid hormones thyroxine (T4) and rT3. Other potential substrates, such as triiodothyronine (T3), 17-beta-glucuronosyl estradiol, estrone-3-sulfate and sulfobromophthalein (BSP) are transported with much lower efficiency. May play a signifiant role in regulating T4 flux into and out of the brain (By similarity); Belongs to the organo anion transporter (TC 2.A.60) family.

Synonyms:  SLCO1C1,  SLCO1C1p,  hSLCO1C1,  F5H6S4,  Q9NYB5 ...

Linkouts:  STRING  Pharos  UniProt