DISEASES

Disease-gene associations mined from literature

Literature associating LPAR2 and triple-receptor negative breast cancer

LPAR2 [ENSP00000443256]

Lysophosphatidic acid receptor Edg-4; Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.

Synonyms:  LPAR2,  LPAR2p,  hLPAR2,  A0A024R7M9,  EDG4 ...

Linkouts:  STRING  Pharos  UniProt