DISEASES

Disease-gene associations mined from literature

Literature associating KLHL13 and benign recurrent intrahepatic cholestasis

KLHL13 [ENSP00000443191]

BTB and kelch domain-containing protein 2; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis; BTB domain containing

Synonyms:  KLHL13,  KLHL13p,  hKLHL13,  C9JTS9,  KLHL13-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM