DISEASES

Disease-gene associations mined from literature

Literature associating SESN3 and endometrial adenosquamous carcinoma

SESN3 [ENSP00000441927]

Sestrin 3; May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity).

Synonyms:  SESN3,  SESN3p,  hSESN3,  F5H1K7,  P58005 ...

Linkouts:  STRING  Pharos  UniProt  OMIM