DISEASES

Disease-gene associations mined from literature

Literature associating TSHR and hyperthyroidism

TSHR [ENSP00000441235]

Thyroid stimulating hormone receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism (By similarity); Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.

Synonyms:  TSHR,  G3V381,  P16473,  Q0VAP8,  G3V381p ...

Linkouts:  STRING  Pharos  UniProt