Literature associating TLR5 and systemic lupus erythematosus
Toll/interleukin-1 receptor-like protein 3; Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response; Toll like receptors
Synonyms: TLR5, TLR5p, hTLR5, B1AZ06, O60602 ...