Literature associating CLEC4C and dilated cardiomyopathy 1C
C-type lectin domain family 4, member C; Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non- sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen- processing and peptide-loading compartments for presentation to T- cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
Synonyms: CLEC4C, CLEC4Cp, hCLEC4C, H0YFH6, H0YGB2 ...