Disease-gene associations mined from literature

Literature associating ANAPC15 and nemaline myopathy 2

ANAPC15 [ENSP00000439403]

Anaphase promoting complex subunit 15; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint. Also required for degradation of CDC20.

Synonyms:  ANAPC15,  ANAPC15p,  hANAPC15,  A0A024R5G0,  C11ORF51 ...

Linkouts:  STRING  Pharos  UniProt