Disease-gene associations mined from literature

Literature associating CYB5R2 and methemoglobinemia

CYB5R2 [ENSP00000437041]

NADH-cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4- disulfophenyl]-2H tetrazolium monosodium salt (WST-1); Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

Synonyms:  CYB5R2,  CYB5R2p,  hCYB5R2,  LOC102723491,  E9PIV9 ...

Linkouts:  STRING  Pharos  UniProt