Literature associating AGBL2 and CREST syndrome
ATP/GTP binding protein-like 2; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.
Synonyms: AGBL2, AGBL2p, hAGBL2, E9PI49, E9PJH3 ...