DISEASES

Disease-gene associations mined from literature

Literature associating CDC27 and cervix carcinoma

CDC27 [ENSP00000434614]

Cell division cycle protein 27 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Synonyms:  CDC27,  CDC27p,  hCDC27,  CDC27-001,  CDC27-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM