Disease-gene associations mined from literature

Literature associating C11orf30 and sporadic breast cancer

C11orf30 [ENSP00000433205]

BRCA2-interacting transcriptional repressor EMSY; Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.

Synonyms:  C11orf30,  B4E247,  E9PMC9,  E9PPE6,  EMSY ...

Linkouts:  STRING  Pharos  UniProt