Literature associating API5 and hereditary desmoid disease
Fibroblast growth factor 2-interacting factor; Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs; Armadillo-like helical domain containing
Synonyms: API5, API5p, hAPI5, B4E283, E9PQK6 ...