Literature associating GPBAR1 and primary sclerosing cholangitis
G protein-coupled bile acid receptor 1; Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.
Synonyms: GPBAR1, GPBAR1p, hGPBAR1, Q8TDU6, Q8TDU6p ...