Disease-gene associations mined from literature

Literature associating GPBAR1 and primary sclerosing cholangitis

GPBAR1 [ENSP00000430886]

G protein-coupled bile acid receptor 1; Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids.

Synonyms:  GPBAR1,  GPBAR1p,  hGPBAR1,  Q8TDU6,  Q8TDU6p ...

Linkouts:  STRING  Pharos  UniProt